Does Multiple Sclerosis Cause Brain Disfunction?


Asked by Marj Weelson

Does Multiple Sclerosis Cause Brain Disfunction?


Hi Marj,

Merely Me provided excellent resources for you to check out. I'm going to go at your question in a different way.

In Multiple Sclerosis, damage is being done to the insulating coating of the nerves (myelin) which sometimes results in damaged nerves. This damage is seen not just in the spinal cord but also in the white matter of the brain.

Any damage to the white matter of the central nervous system can affect functions of the brain and body. Here's an Introduction to Brain Dysfunction from the Merck Manual. Memory and mood can definitely be affected.

Damage to the front part of the frontal lobe in the brain can result in:

  • Impaired concentration

  • Reduced fluency of speech

  • Apathy

  • Inattentiveness

  • Delayed responses to questions

  • A striking lack of inhibition, including socially inappropriate behavior People who lose their inhibitions may be inappropriately euphoric or depressed, excessively argumentative or passive, and vulgar. They may show no regard for the consequences of their behavior. They may also repeat what they say.


The brain's mechanisms for storing information and recalling it from memory are located primarily in the temporal and frontal lobes, but many areas of the brain are involved in memory. Emotions originating from the limbic system can influence the storing of memories and their retrieval. The limbic system includes part of the cerebrum and some structures deep within the brain. Areas that are responsible for alertness and awareness in the brain stem also contribute to memory. Because memory involves many interwoven brain functions, virtually any type of brain damage can result in amnesia.

I hope that this helps in your search for answers. I look forward to talking with you again.


Answered by Lisa Emrich