Effexor Xr And Liver Function Tests


Asked by Greg

Effexor Xr And Liver Function Tests

Has anyone had any experience with elevated liver enzyme tests while taking Effexor XR? I was denied some life insurance based on a blood test that showed slightly elevated liver enzymes. I want to reapply for the insurance, but I have to be able to explain the elevated tests. I have no symptoms and no other risk factors for liver disease, or for anything else (except depression, which was not the reason for the denial). I discussed with my doctor. He did an exam and ordered hepatitis tests which all came back negative. I'm super healthy. The doctor did say that elevated liver enzymes are not listed as a major side effect of Effexor. Anyone seen this before?



Although the listed side effects for Effexor don't include any issues with the liver, there is a mention of liver function in the postmarketing reports printed in the prescribing information for Effexor XR. Here's an excerpt:

"Postmarketing Reports
Adverse Events
Voluntary reports of other adverse events temporally associated with the use of venlafaxine that have been received since market introduction and that may have no causal relationship with the use of venlafaxine include the following:... abnormalities of unspecified liver function tests..."

Other than that, I've not seen or heard anything about Effexor and liver function.

Hope this helps,


Answered by Teri Robert