High Sugar Intake Linked to Alzheimer's Risk
A recent study showed a connection between high blood glucose levels—hyperglycemia—and Alzheimer's disease risk. Researchers in Australia discovered a molecular link between glucose and Alzheimer's—specifically that high blood sugar can damage an important enzyme involved in brain inflammation in the early stages of Alzheimer's disease.
Hyperglycemia is characteristic of both diabetes and obesity. Earlier research proved that people with diabetes are at increased risk for Alzheimer's disease—a condition in which abnormal proteins accumulate in the brain and form plaques and tangles—and that blood glucose and its byproducts damage cell proteins through a process known as glycation.
In this recent study, scientists determined that glycation damages macrophage migration inhibitory factor (MIF) enzymes in early Alzheimer's. According to researchers, we now have yet another reason to limit the amount of sugar in our diets.
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