Can Humira Slow Bone Healing After A Fracture/break?


Asked by Impulze

Can Humira Slow Bone Healing After A Fracture/break?

Hi, I am a 32 yr old male who was finally diagnosed wit AS after 12 yrs of suffering. I am currently taking Humira which I have say has giving me the best quality of life I can remember for a long time :-). The question I have is that I have recently broken my wrist and had plate attached. Humira was advised to be stopped whilst wound was healing, but I am worried about continuing treatment, my main concern is that will it slow down the bone healing process? Tha reason I ask this is because Humira ( TNF- inibitors ) stop or slow joints etc fusing together, which in my opinion is a natural process in bone healing after fracture/break.

Thanks for any answers in advance Gavin

p.s I know this is a RA site, but on my searching it came the closest to answering my question.


Yes, we specialize in RA, but we do have a number of people who have AS, so I'll do my best. We are planning to have more AS content, so if you're up to it, would you mind telling me a bit about what would be helpful information for us to have?

The processes involved in healing a fracture and a joint fusing due to various forms of arthritis is due entirely to different things. A bone knitting back together is a natural healing process, whereas a joint fusing due to arthritis is very definitely not. I suspect that it was recommended that you skip Humira while you heal due to the possibility of infection -as is medication is an immunosuppressant, you would be more vulnerable to infection, with which would be a very bad idea to happen in the bone. I would definitely recommend that you contact the doctor treating your AS or your surgeon to get more information.

Good luck! Please let us know how things go?

Answered by Lene Andersen, MSW