Link found between diabetes and Alzheimer's
A new study from Washington University in St. Louis provides more evidence of a possible connection between diabetes and Alzheimer’s disease. This latest research found that elevated blood sugar levels in mice can significantly increase the amount of amyloid beta—a type of brain plaque associated with Alzheimer’s. The findings were published in The Journal of Clinical Investigation.
Researchers injected sugar into the blood stream of mice genetically bred to develop an Alzheimer’s-like condition. When the blood sugar levels in mice doubled, the mice without amyloid beta in their brains showed a 20 percent increase in amyloid beta. Older mice that already had some brain plaque showed a 40 percent increase in amyloid beta when their blood sugars were doubled.
The researchers also found that spikes in blood sugar increased the neuron activity in the brain, thus triggering amyloid beta production. Brain cells need to fire in order to transmit information, but excessive firing in certain parts of the brain can cause increased amyloid beta production and plaque buildup.
More research is being conducted by the team to explore this connection. The researchers hope that it could lead to future treatments to reduce the effect of diabetes on Alzheimer’s.
NEXT: Money problems double women’s risk of heart attacks
Sourced from: sciencedaily.com, New link between diabetes, Alzheimer’s found
Published On: May 5, 2015
Researchers recommend two-minute walk every hour
If you’re worried that your lifestyle has become too sedentary, here’s what new research says you should do about it: Take a two-minute walk every hour.The National Institute of Diabetes and Digestive Kidney Diseases (NIDDK) and the University of Utah Study Design and Biostatistics Center helped fund the study, which was published in the Clinical Journal of the American Society of Nephrology..
To better understand an effective solution to sedentary lifestyles, researchers analyzed 3,243 participants in the 2003-2004 National Health and Nutrition Examination Survey (NHANES). Participants wore accelerometers for several days to better track their mobility. The study tracked participants for three years, and 137 of them died during the study period.
Based on the accelerometers, researchers calculated the average minutes per hour spent either sedentary (less than 100 accelerometer counts per minute), low activity (100-499), light activity (500-2019), or moderate to vigorous activity (2020 and over). They then looked at the mortality risks if these minutes were reduced by two per hour. They found no benefits of standing for two minutes instead of sitting for two minutes. However, they found a 33 percent decreased risk in early death if someone walked or did light activity, such as gardening, for two minutes instead.
Researchers noted the findings were promising for people who can’t or don’t want to increase their activity by doing moderate or vigorous exercise—which is often the recommendation. Little changes of light movement can add up over time, and based on these findings, the researchers suggested people walk for two minutes each hour.
The study does not prove that walking two minutes every hour can prevent early death, but it does show a strong association between the two.
NEXT: How anxiety affects your health (INFOGRAPHIC)
Sourced from: medicalnewstoday.com, Two-minute walk every hour may reduce hazard of prolonged sitting
Published On: May 5, 2015
Money problems double women's risk of heart attacks
Women stressed out by money problems have an increased risk of suffering a heart attack, according to a new study at the University of California Medical Center in San Francisco.
Researchers analyzed the Women’s Health Study, a survey that documented participants over a nine-year period. They looked at 267 women with an average age of 56 who experienced a heart attack at some point during the study period. For comparison, they also looked at 281 women with similar risk factors, such as smoking, who did not have a heart attack.
When the survey started, participants answered questions about stressful life situations, such as injury or unemployment, during the previous five years. Three survey options were classified as “traumatic”: a life-threatening illness, a serious assault, or the death of a child or spouse.
The results showed that women with financial woes doubled their risk of heart attack, and women making under $50,000 were at an increased risk for stressful events overall. A traumatic event increased heart attack risk by 65 percent, regardless of income.
Previous research has shown that women tend to have worse recovery from heart attacks than men. Heart disease is currently the number one cause of death in women, according to the Centers for Disease Control and Prevention. Yet it’s still unclear what factors contribute to heart attacks in women with no previous heart conditions. These new findings highlight the need for further gender-specific research on heart disease risk factors, particularly for women of lower socio-economic status.
NEXT: Researchers recommend two-minute walk every hour
Sourced from: livescience.com, Financial Stress Can Take a Toll on Women’s Hearts
Published On: May 5, 2015