Male Child 14 Years Calf Muscle Pain After 3 Days Of Viral Fever Now Having High Blood Cpk Value

Question

Asked by deepak999

Male Child 14 Years Calf Muscle Pain After 3 Days Of Viral Fever Now Having High Blood Cpk Value

My son had a fever for 3 days and now he has pain /cramps in his calf muscles. His CPK levels are elevated. He's just 14 years old and is an active & normal child. We don't understand why is his CPK levels are high? He has had similar symptoms of calf muscle pain just after viral fever twice before. Can anyone advise us as to what can cause this?

Answer

The high CPK is most likely related to Rhabdomyolysis caused by the viral infection.

Rhabdomyolysis is a term used to describe the breakdown of striated muscle. Cells in the muscle break down and are released into the blood stream. The most common cause of this is muscle injury, but it can be caused by drugs, toxins, and bacterial and viral infections, among other things.

The most classic symptoms are muscle pain and weakness and dark urine, although not all sufferers have these symptoms. Fever itself is a symptom of Rhabdomyolysis, so your son may not be having re-occuring "viral infections", just re-occurring Rhabdomyolysis maybe from exertion ("active child"), called exertional Rhabdomyolysis.

So, additionally, you may want to have your son checked for sickle cell trait which is commonly associated with re-occuring incidences of Rhabdomyolysis. I answered a similar question just recently about this condition.

Please stay in close contact with your son's doctors in order to avoid complications like kidney damage from the high protein levels (CPK levels) in the blood. It may be time to see a specialist.

Answered by Christina Lasich, MD