I have good news for those of you who depended on Midrin for Migraines or tension-type headaches. I’ve confirmed that Macoven Pharmaceutical out of Magnolia, Texas, is producing and shipping their Midrin equivalent medication across the United States.
The problems with Midrin and other medications equivalent to Midrin have been going on for nearly a year now. Midrin was introduced long enough ago that it predated the current FDA drug approval process. During the many years between the time that the FDA approval process went info effect and the time that Midrin was discontinued, none of the pharmaceutical companies producing these medications did the required clinical trials and applied for FDA approval. So, first Midrin was discontinued, then the equivalent medications - medications with the same ingredients - were pulled from the market. Since Midrin was never approved by the FDA, there technically weren’t generics; there were equivalent drugs. For more background on this, including a copy of the email explanation I received from the FDA, see _Midrin for Migraine: What’s Going On? _
When I heard that Macoven was producing and shipping a medication equivalent to Midrin, I called their customer service number and spoke with a woman named Cindy. She confirmed that they are indeed producing and distributing a medication equivalent to Midrin. They distribute across the U.S., and pharmacists should be able to get their Isometh/Dich/Apap capsules. Those abbreviations stand for isometheptene mucate, dichloralphenazone, and acetaminophen Cindy was well aware of the situation with these medications and the FDA. She told me that Macoven is “working with the FDA” to be able to keep their product on the market.
I find this encouraging, but I’m going to be cautious about being too encouraged until Macoven has officially worked things out with the FDA. You may remember that two other pharmaceutical companies have worked with the FDA over the last year to keep their products on the market, and they ended up discontinuing their Midrin equivalent medications.
Since so many Migraineurs have depended on Midrin and equivalent medications, I’ll be checking in with Macoven periodically to see what progress they’ve made with the FDA and will post updates whenever I have new information.
Teri Robert is a leading patient educator and advocate and the author of Living Well with Migraine Disease and Headaches. A co-founder of the Alliance for Headache Disorders Advocacy and the American Headache and Migraine Association, she received the National Headache Foundation’s Patient Partners Award and a Distinguished Service Award from the American Headache Society. Teri can be found on her website, and blog, Facebook, Twitter, StumbleUpon, Pinterest, LinkedIn, and Google+.