Midrin for Migraine and Tension-Type Headache - Definitely Discontinued

Patient Expert

Over the last few years, there have been problems getting Midrin. Midrin is a medication used as a Migraine abortive and for the relief of tension-type headaches.

At one point, Caraco, the manufacturer of Midrin, was having problems getting some of the ingredients in Midrin. Once the shortage was resolved, the manufacturing of Midrin was resumed.

More recently, people have once again reported that their pharmacies couldn't get Midrin. Some pharmacists said it was discontinued; others said it was just out of stock. To get to the bottom of this problem I called and talked with someone at Caraco this week. The "official" word is that Midrin was discontinued in October of 2009, and it will not be manufactured again. If you've managed to get Midrin after October, it was from shipments manufactured prior to the medication being discontinued.

The news isn't all bad though. One of our members, Mary-Lynn, reports that her pharmacy filled her prescription with "Isometh-D-Chloralphenz-AP APITP." Her prescription label also says, "Generic Equivalent for Midrin Capsule."

Midrin is a compound medication containing acetaminophen, dichloralphenazone, and isometheptene mucate. Acetaminophen is a simple analgesic (a simple pain reliever}. Dichloralphenazone is a mild sedative that slows down the central nervous system. Isometheptene reverses the dilation of blood vessels that occurs during a Migraine.

For those of you who are trying to get Midrin or are considering trying Midrin, hopefully, this information will make things easier for you.

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Medical review by John Claude Krusz, PhD, MD.