Migraine Term of the Day: Neuropeptide

Patient Expert
Medically Reviewed

Writer’s note: Some of you have expressed an interest in learning more of the medical terminology that comes up when discussing Migraine disease and other headache disorders. So, I’ll be posting a “term of the day” on a regular basis. If there are terms you’d like to have defined, please leave a comment below.

When we’re given Migraine and headache information, whether from our doctor, a book, or an online article, we sometimes come across medical terms that can be confusing. While it’s easy enough to substitute another word or a short phrase for the medical term, there are times when substituting doesn’t quite convey the same meaning.

Neuropeptide is one of those terms. We see it used when talking about Migraine treatments, new Migraine treatments under development, clinical trials, and it’s an important word for patients with Migraine to understand.


A neuropeptide is a small endogenous protein-like molecule that acts as a neurotransmitter.

Here’s an example of how it’s used in a sentence:

The neuropeptide CGRP is at the center of the development of a new class of Migraine preventive therapies.

See more helpful articles:

New CGRP Monoclonal Antibody Migraine Preventives

New Class of Migraine Preventives Raises Excitement and Hope