Can I Mix 10MG of Ambien with 50MG of Diphenhydramine?


Asked by Fiddle dreamer

Can I Mix 10 Mg Of Ambien With 50 Mg. Of Diphenhydramine? (In Simply Sleep & Benadryl)

10 mg of Ambien was taken 2 1/2 hrs ago to help induce sleep. I am still awake and now wondering if taking 50 mg of diphenhydramine (in the form of Tylenol Simply Sleep) would be dangerous? I've also consumed 2 beers over the last 6 hours.

Any facts would be much appreciated. I've tried searching briefly and haven't found an answer yet.



Dear Fiddle Dreamer,

Your best bet would be to call a 24 hour pharmacy and speak to a pharmacist. I did a search as well, and it appear that mixing the two is not a good idea, but like I said, you can consult with a pharmacist even at a very late hour!

For future nights, please check out our CD at The Stress Masters website, we've had many, many people tell us that it is useful for falling asleep!


Jennifer L. Fee, Psy.D.

The Stress Masters

*Jennifer Fee, Psy.D. is a Psychologist, not a Psychiatrist. Psychiatrists prescribe medications, Psychologists study them, but the majority of Psychologists are not authorized to prescribe meds. or give you specific advice about them. Dr. Fee's answers are not intended to diagnose or treat any medical or mental disorder. Any information given in a post about medication is for educational purposes only, and primarily to aid you in having an informed discussion with your own Psychiatrist/Physician.

You should know: The answer above provides general health information that is not intended to replace medical advice or treatment recommendations from a qualified healthcare professional.