Nanotech delivers vaccines without needles
A nanotech-based vaccine that can be applied to the body's mucus membranes could be a more effective way of vaccinating people against infectious diseases without using needles, according to a new study in mice.
The research, published in the journal Science Translational Medicine, found that nanocapsules loaded with a vaccine and deposited in the mice's airways were able to get past the mucosal barrier, enter the bloodstream, and create an immune response in the animals.
The mucosal surfaces of the body – which cover the insides of the nose, lungs and reproductive tract--are where many pathogens enter the body. While sprays can be used to administer vaccines, the lungs often clear it away before it can provoke an immune response.