How Many Naproxen Can You Safely Take At One Time?


Asked by Tisha

How Many Naproxen Can You Safely Take At One Time?

I have 500 mg Naproxen tablets. How many can I safely take at once?


500 mg is the most that should be taken at any one time, with a maximum of 1500 mg per day. It should not be taken on a regular basis for more than 6 months.

Naproxen has some pretty serious black-box warnings on it, so it's important not to take any more than necessary and to use it for the shortest duration possible. Following are the black-box warnings:

Cardiovascular Risk:

Naproxen may increase the risk of serious and potentially fatal cardiovascular thrombotic events, myocardial infarction, and stroke; risk may increase with duration of use; possible increased risk if patient has cardiovascular disease or cardiovascular disease risk factors; contraindicated for Coronary-Artery Bypass Grafting Surgery peri-operative pain.

GI Risk:
Naproxen increases the risk of serious gastrointestinal adverse events including bleeding, ulceration, and stomach or intestine perforation, which can be fatal; may occur at any time during use and without warning signs; elderly patients are at greater risk for serious GI events.

If this medication won't relieve your pain it's important to talk to your doctor about other medications. In the meantime, these articles may give you other pain-relieving ideas.

Five drug combinations to help chronic pain

Why yoga may soothe many times of chronic pain
The Most Common Reasons that the Pain is Getting Worse

You should know: The answer above provides general health information that is not intended to replace medical advice or treatment recommendations from a qualified healthcare professional.