Nasal spray treatment developed for migraines
Researchers from the Roseman University of Health Sciences say they're developing a nasal spray that could treat migraines. They reported their results this week at the annual meeting of the American Association of Pharmaceutical Scientists in San Diego.
The new prochlorperazine spray is preservative-free, and so it does not have any of the preservative associated side-effects such as mucosal irritation. The formula is also the first to use prochlorperazine as a spray instead of in the more commonly-used pill form for the treatment of migraines.
Prochlorperazine, mostly used as an anti-nausea medication, works against dopamine receptors to provide better pain relief than many other anti-migraine medications. Using the drug as a spray is significant in that it is not only fast-acting, but the formula has already shown it can be used for up to 120 days. The researchers say they next plan to test the spray on rats.
More than one-third of the 100 million people in the U.S. who get headaches suffer from migraines.