Researchers from the University of Sheffield’s Department of Infection, Immunity and Cardiovascular Disease in England have discovered a biomarker that could help identify patients at increased risk after a heart attack. This discovery could lead to new treatments for reducing heart disease risk in these patients.
In this study, the researchers analyzed blood plasma samples from more than 4,300 patients with acute coronary syndrome upon discharge from the hospital. They measured blood clot lysis time – maximum clot density and the amount of time it takes for a blood clot to break down – in these patients and adjusted their findings for known risk factors and clinical characteristics. According to researchers, patients with the longest clot lysis time had a 40 percent higher risk for recurrent heart attack or death due to cardiovascular disease.
Results of this study suggest that targeting clot lysis could improve outcomes in people with acute coronary syndrome. The findings were published in the European Heart Journal.