New Guidelines for Mild-to-Moderate Ulcerative Colitis Treatment

by Diane Domina Senior Content Production Editor

The American Gastroenterological Association has published new clinical guidelines for treating mild-to-moderate ulcerative colitis (UC), an inflammatory bowel disease (IBD). Mild-to-moderate UC, characterized by periods of disease activity followed by periods of remission, is defined by these symptoms:

  • Fewer than four to six bowel movements per day

  • Mild or moderate rectal bleeding

  • Absence of symptoms like fever, fatigue, weight loss, or malaise

  • Low, rather than high, levels of inflammatory activity

The new guidelines, published in Gastroenterology, focus on the use of oral and topical 5-aminosalicylates (5-ASA) medications (sulfasalazine, mesalamine, balsalazide, olsalazine), rectal corticosteroids, and oral budesonide (Entocort EC, Uceris). People with ulcerative colitis who don’t respond to these therapies may require a stronger medication regimen, but the new guidelines don’t address these treatments.

Sourced from: Gastroenterology

Diane Domina
Meet Our Writer
Diane Domina

Diane works across brands at Remedy Health Media, producing digital content for its sites and newsletters. Prior to joining the team, she was the editorial director at HealthCommunities.