New Treatment Reduces Severe Asthma Symptoms

by Diane Domina Senior Content Production Editor

A new treatment for severe asthma could improve lung function and reduce the need for corticosteroids by as much as 70 percent, according to researchers from McMaster University’s Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton in Ontario, Canada, who developed the therapy.

The Canadian researchers conducted a study involving more than 200 participants who had been using oral corticosteroids (prednisone) for severe asthma symptoms for at least six months. In addition to their standard treatment regimen, the study participants were given either dupilumab or a placebo for 24 weeks. The prednisone dose was gradually reduced from week 4 to 20, and then maintained.

Dupilumab reduces asthma symptoms by blocking two specific proteins associated with airway inflammation, according to researchers. Corticosteroids can cause serious side effects – especially when used for prolonged periods of time – so it’s important to develop safe, effective alternatives to treat severe asthma.

Sourced from: New England Journal of Medicine

Diane Domina
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Diane Domina

Diane works across brands at Remedy Health Media, producing digital content for its sites and newsletters. Prior to joining the team, she was the editorial director at HealthCommunities.