Researchers at the University of Waterloo in Ontario, Canada, say they’ve developed a new way to treat chlamydia (Chlamydia trachomatis) — the most common bacterial STI (sexually transmitted infection) worldwide. In laboratory studies, a single dose of this investigative treatment, which involves gene therapy delivered via nanotechnology, was 65 percent effective at preventing chlamydia infection.
In the laboratory, the researchers used a type of RNA to target a gene in the female reproductive tract that creates a protein that binds to Chlamydia bacteria. Using this process prevented most of the bacteria from entering cells in the genital tract and destroyed bacteria able to penetrate a cell wall.
Chlamydia is generally curable with antibiotics, but the sexually transmitted disease often goes undiagnosed and, like other STDs (gonorrhea and syphilis, for example), is becoming more difficult to treat due the growing problem of antibiotic resistance, according to the World Health Organization (WHO). Untreated chlamydia can cause infertility and other serious complications in both men and women.
Sourced from: Scientific Reports