Pancreatic cancer risk may be up to four times higher in adults who were overweight or obese during adolescence, according to a study published in Cancer and conducted by researchers at Rabin Medical Center and Tel Aviv University, both in Israel.
The researchers analyzed data on more than a million men and more than 700,000 women who underwent physical exams between ages 16 and 19 from 1967 to 2002. They identified pancreatic cancer incidence through 2012 using the Israeli National Cancer Registry. During the average 23-year follow-up, 551 study participants — 423 men and 128 women — were diagnosed with pancreatic cancer.
According to the researchers, adults whose weight had been above the 95th percentile when they were teens were at higher risk for pancreatic cancer — 3.67 times higher in men, 4.07 times higher in women. In men, increased risk was also found in those with “high-normal” teen weights (>75th to <85th percentile) and those classified as overweight (85th to <95th percentile). The increased pancreatic cancer risk in these men ranged from 49 percent to 97 percent higher.
Sourced from: Cancer