Pathophysiology is functional changes associated with or resulting from disease or injury and the study of those changes.
When related to Migraine attacks, the pathophysiology of a Migraine attack would mean the changes in how the brain and central nervous stem function when a Migraine is triggered and during the Migraine attack. We could discuss the pathophysiology of how the triggers themselves work – what changes occur when we encounter a trigger. We could discuss the pathophysiology of a Migraine attack – what happens to the blood vessels, the nerves and tissues surrounding the blood vessels, the levels of neurotransmitters such as serotonin and norepinephrine.
All of these discussions would be about the pathophysiology of Migraine, something that is still not fully understood. Researchers are making advances, however. The most recent article we published about Migraine research that was related to pathophysiology is Why Hangovers May Be Worse for Migraine Sufferers.
Teri Robert is a leading patient educator and advocate and the author of Living Well with Migraine Disease and Headaches. A co-founder of the Alliance for Headache Disorders Advocacy and the American Headache and Migraine Association, she received the National Headache Foundation’s Patient Partners Award and a Distinguished Service Award from the American Headache Society. Teri can be found on her website, and blog, Facebook, Twitter, StumbleUpon, Pinterest, LinkedIn, and Google+.