An international team led by researchers from the University of Virginia School of Medicine in Charlottesville, Virginia, have identified new genetic risk factors associated with stroke and related conditions, such as atrial fibrillation, hypertension, high cholesterol, coronary artery disease, and blood clots. This information could help lead to new targeted treatments and prevention strategies.
For the study, researchers analyzed data on DNA samples from 520,000 people involved in 29 large studies around the world, 67,000 of whom had had strokes. The researchers identified 32 independent genomic regions associated with stroke – 22 of which were previously unknown.
Research groups in 20 countries were involved in this study. Results were published in Nature Genetics.