Skin test may detect Alzheimer's early
Could it be possible to detect debilitating conditions, such as Alzheimer’s and Parkinson’s disease, early through a simple skin biopsy? A team of scientists at the University of San Luis Potosi in Mexico say their research suggests that kind of test may allow doctors to diagnose the illnesses before there’s an irreversible loss of brain tissue.
Since skin originates from the same tissue as the brain in the developing embryo, the researchers wanted to take a closer look at what it might reflect about the condition of a person’s brain. They also knew that analysis of the skin of dead people who had Parkinson’s showed the same protein deposits that are in the brain.
They recruited 65 participants–12 were healthy, while 53 had Parkinson’s, Alzheimer’s, or another type of dementia. After taking a small skin biopsy from behind the participants’ ears, they found 20 people with Alzheimer’s and 16 people with Parkinson’s had raised levels of two specific proteins, tau and alpha-synuclein. Those proteins have been associated with either Alzheimer’s or Parkinson’s disease.
The scientists said that more extensive research needs to be done on the skin test, but if it is found to be effective, it could be a minimally invasive way to diagnose and begin treatment of these brain conditions before too much damage is already done.
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Sourced from: BBC, Skin may help spot Alzheimer’s and Parkinson’s disease
Published On: Feb 25, 2015
Big breakfast, light dinner may help fight diabetes
A key to controlling your blood sugar may be as simple as switching up how much you eat at what time, if you are living with type 2 diabetes.
An international team of researchers examined how post-meal blood glucose spikes were reduced when obese non-diabetic people followed a routine of a high-energy breakfast and low-energy dinner. This new study analyzed 18 people (eight men and 10 women) living with type 2 diabetes for less than 10 years. Their ages ranged from 30 to 70 and all were treating their condition with metformin and/or dietary changes. People were randomly given a selection of two diets to follow, one with a high energy breakfast and a low energy dinner, and one with a low energy breakfast and a high energy dinner. Both diets contained the same total energy but were simply scheduled differently. Participants followed their respective diets for six days, and completed their 7th meal in the clinic. Their blood samples were collected just before breakfast and every several minutes after they had started eating.
The results showed that post-meal glucose was 20 percent lower and levels of insulin were 20 percent higher in people who partook in the big breakfast/light dinner diet compared with the other one, despite the fact that both meal plans contained the same total energy and calories during lunch.
These findings show the significant role meal timing can play in controlling blood sugar, according to the researchers, and could help people with type 2 diabetes been more effective in managing their conditions.
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Sourced from: ScienceDaily, High-energy breakfast with low-energy dinner helps control blood sugar in people with type 2 diabetes
Published On: Feb 25, 2015