According to an analysis of 28 clinical trials, statin therapy lowers the risk of major cardiovascular events like heart attack and stroke, even in people over 75. Results of this research, published in The Lancet, aren’t fully in line with guidelines from the U.S. Preventive Services Task Force, which state that:
“The current evidence is insufficient to assess the balance of benefits and harms of initiating statin use for the primary prevention of CVD events and mortality in adults 76 years and older without a history of heart attack or stroke.”
The randomized controlled trials involved a total of 186,854 patients, 14,483 of whom were 75 and older. According to the researchers, each 18 mg/dL reduction in cholesterol cut the risk of major cardiovascular events by about 24 percent overall, from 30 percent in people under 55 to about 20 percent in those over 75.
Previous studies have shown that the benefits of statin drugs outweigh the risk of adverse side effects, which can include muscle problems (myopathy).
Sourced from: The Lancet