Testosterone Treatment May Help Men with Diabetes
A study published in Diabetes Care concludes that men with type 2 diabetes and low testosterone levels can benefit significantly from testosterone treatment.
Researchers at the Jacobs School of Medicine and Biomedical Sciences at the University of Buffalo had already determined in a 2004 study that low testosterone levels coincide with significantly decreased insulin sensitivity.
Six years later, they extended this to adult obesity, and in 2012, the team found that teenage boys with obesity have 50 percent less testosterone than their lean peers.
The newest study involved 94 men with type 2 diabetes, of whom 44 had low testosterone levels. The men with low testosterone were randomized to receive a testosterone injection or a placebo every week for 24 weeks.
The results: Testosterone did not change the men's body weight, but there was a reduction in total body fat of more than six pounds, while muscle mass increased.
There was also a dramatic increase in insulin sensitivity, demonstrated by a 32 percent increase in the uptake of glucose by tissues in response to insulin.
The researchers now want to see how testosterone treatment may affect insulin resistance and inflammation in patients with specific conditions, such as those with chronic renal failure and hypogonadism.
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