The Link Between Heredity and Heart Failure Risk


Researchers in Sweden evaluated heart failure risk in adults who were adopted — comparing the risk in relation to biological parents and adoptive parents — to assess the impact of genetic and environmental factors on heart failure risk. They determined that heredity is the dominant factor in families they studied.

Researchers at Lund University assessed 21,643 adoptees born between 1942 and 1990 and a control group. They tracked heart failure incidence in the adoptees and their biological parents between 1964 and 2015, as recorded in the Swedish National Patient Register.

They found that heart failure risk in adopted adults with at least one biological parent who had the condition was 45 percent higher than it was for those in the control group who didn’t have a biological parent with heart failure. They also found no increased heart failure risk in those whose adopted parents had heart failure, compared to the control group. Overall, the researchers found that genetic factors play a role in about 26 percent of heart failure cases in Sweden.

Sourced from: JAMA Cardiology