UK researchers grow teeth in mice
UK researchers may have found a way to regrow human teeth using both human cells and mouse cells. A team of scientists at King’s College London developed a technique that combines epithelial cells from human gum tissue and mesenchyme cells from mice to grow a hybrid mouse/human tooth with viable roots.
The teeth grow and thrive because the mesenchyme cells from the mice are cultured to be ‘inducing’, which means they instruct the human epithelial cells to grow a tooth.
The new research proves the technique is possible, but without a ready supply of cultured mesenchyme cells, it is very expensive and impractical for clinical use. Further research will focus on finding a more readily accessible source of human mesenchyme cells.