Why Does Most Pain Medication Make Me Itch


Asked by Kathy

Why Does Most Pain Medication Make Me Itch

Most pain medication make me itch to some degree. I get hives from percocet, but others just make my skin itch


Many people do not realize that most types of opiate medications, pain medications cause a release of histamine in the body. The histamine causes itchiness, nausea, headaches, nausea, or hives/rashes.

Using an anti-histamine (benadryl or vistaril) 30 minutes prior to taking the pain medication relieves these common side effects.

Some medications cause less histamine release than others, so talk to your doctor to find better solutions.

Dr. Christina Lasich, MD

Answered by Christina Lasich, MD