Why Is It Not Safe To Take Seroquel And St. John's Wort Together?

Question

Asked by gina

Why Is It Not Safe To Take Seroquel And St. John's Wort Together?

About a month ago i was diagnosed with bipolar disorder. My doctor prescribed me Seroquel XR. Along with that i began to take omega 3 fish oil, a weight consciece vitamin, and St. John's wort. i was beginning to feel better, but then I was advised by my therapist, doctor, and pharmasist to stop taking the St. John's wort so i did but almost immediately i began to feel my syptoms come back worse than before. it seems as though the St. John's wort was helpin me more than the seroquel is. What do i do?

Answer

Seroquel and St. John's wort taken together can cause serotonin syndrome, which can be a serious condition. Symptoms can include fever, a slow or racing pulse, sudden jerking movements, rigid muscles, rapid heartbeat, high blood pressure, rapid breathing, high blood pressure and more.

For the same reason, St. John's wort shouldn't be used with an antidepressant that increases serotonin levels.

There is also some indication that St. John's wort has the potential to trigger mania or hypomania.

~Marcia

Bipolar Expert - Living With It

Answered by Marcia Purse