https://www.healthcentral.com/condition/wet-amd-treatment
AMDWet AMDWet AMD Treatment

Let's Talk About Wet Age-Related Macular Degeneration Treatment

It's a serious disease—with highly successful treatment options. Here's what the experts say is your best approach if you've been diagnosed with wet AMD.

    Our Pro PanelWet AMD Treatment

    We went to some of the nation's top retina specialists in ophthalmology to bring you the most up-to-date information possible.

    Jason Hsu, M.D.

    Jason Hsu, M.D.Retina Specialist, Attending Surgeon

    Wills Eye Hospital
    Philadelphia, PA
    Rukhsana G. Mirza, M.D.

    Rukhsana G. Mirza, M.D.Retina Specialist, Associate Professor of Ophthalmology and Medical Education

    Feinberg School of Medicine at Northwestern Medicine
    Chicago, IL
    Timothy G. Murray, M.D.

    Timothy G. Murray, M.D.President

    American Society of Retina Specialists
    Miami, FL
    Wet AMD Drugs: Positive Results After 5 Years
    Age-Related Macular Degeneration

    In Your Sights: Wet AMD

    We've got all of the information you need to tackle this disease, including what to eat, questions to ask your doctor, and how to make your day a little bit easier.

    close up of eye
    Age-Related Macular Degeneration

    What Every Person Over 50 Needs to Know About AMD

    Get doctor-approved answers for all of your AMD questions.

    Frequently Asked QuestionsWet AMD Treatment

    What is wet AMD?

    Also called neovascular AMD (or age-related macular degeneration), this type of eye disease is a progression of dry AMD. Wet AMD is the late stage of the disease, with a major impact to the macula, which is responsible for the central part of your vision.

    What’s the current treatment for wet AMD?

    First-line treatment for wet AMD is called anti-VEGF therapy. This medication targets the VEGF protein in your eye involved in blood vessel growth, aiming to stop new, weak vessels from growing. Anti-VEGF drugs are given as a shot in the eye.

    Can lasers treat wet AMD?

    Prior to the approval of the first anti-VEGF therapy for wet AMD in 2004, two laser therapies were available, first laser photocoagulation surgery and then photodynamic therapy (PDT), but they weren’t effective for all wet AMD patients, and had real issues involved in their treatment. Anti-VEGF is the more common treatment now.

    What new treatments are on the horizon?

    Experimental treatments (not yet FDA-approved) include a small implant in the wall of the eye that releases anti-VEGF medication for up to 15 months before it needs to be refilled. Another approach uses gene therapy to block VEGF production for years. And new drugs are being developed to enhance the effectiveness of anti-VEGF meds.

    Erin L. Boyle

    Erin L. Boyle

    @ErinLBoyle

    Erin L. Boyle, the senior editor at HealthCentral from 2016-2018, is a freelance medical writer and editor.