People with Relapsing-Remitting Multiple Sclerosis (RRMS) have clearly defined flare-ups (also called relapses, attacks, or exacerbations). These are episodes of acute worsening of neurological function. They are followed by partial or complete recovery periods (remissions) free of disease progression.
Attacks of Relapsing-Remitting MS can include vertigo, blindness, gait instability, paralysis, numbness, hair loss and confusion.
Fatigue and Disability are always correlated with Brain MRI and type of initial neurological features in patients with Relapsing Remitting MS
Primary Progressive Multiple Sclerosis (PPMS) can follow a Relapsing-Remitting MS presentation
Demyelination is an inflammation mediated attack on the white matter in patients with Relapsing-Remitting MS