“The majority of melanomas are anywhere from black to grayish dark brown,” Dr. Wendel says. Normal moles can vary in color, but if you see multiple colors or shades of tan, black, and brown in one single mole, it’s a sign that something may be off. Red, white, and blue may also appear in a mole that contains melanoma. It’s rare, but sometimes cancerous moles can have no pigment at all, called amelanotic melanoma. “They just look like skin-colored or pink bumps,” Dr. Chon says. While they lack pigment, they may show some of the other melanoma warning signs.