Talk with your doctor to make sure there are no underlying medical causes. Knowing there is nothing wrong may help you relax when you do get palpitations. Besides possible heart conditions, there are other health issues that may cause palpitations. Among them are anemia, low blood pressure, dehydration, and an overactive thyroid condition. Hormonal changes in women, during menstruation, pregnancy, and perimenopause, can also cause palpitations.