Breast Cancer Survivors: 10 Things To Guard Against

by PJ Hamel Patient Expert

A clean bill of health after a fierce battle with breast cancer is a wonderful thing. But it's important to stay on guard for other conditions that breast cancer survivors have an increased risk of developing.

Ultrasound image of lower abdomen, ovary and uterus with tumor

Endometrial/Uterine Cancer

The issue: Taking tamoxifen, a long-term hormone therapy drug given to many survivors, increases the risk of endometrial and other uterine cancers.

Your response: Ask your doctor about the warning signs of these cancers; report any symptoms to your oncologist.

Woman receiving lymphedema therapy


The issue: Radiation and removal of lymph nodes increases the risk of lymphedema, a painful swelling of the trunk and arm that, if untreated, can lead to cellulitis.

Your response: Be careful not to injure your arm on the side where you had surgery. Guard against cuts, burns (including sunburn), insect bites, and muscle injuries or fatigue. Report any swelling to your doctor.

Woman recovering after laparoscopic ovarian surgery

Ovarian Cancer

The issue: Survivors of breast cancer may be at higher risk for ovarian cancer, due to a possible genetic link between the two diseases, according to the American Cancer Society.

Your response: Ask your doctor if you’re a candidate for genetic testing to determine if you’re at higher risk for ovarian cancer. If testing determines you’re at higher risk, consider removal of your ovaries and fallopian tubes.

Close up of a heartbeat on a machine

Cardiac Issues

The issue: Breast cancer survivors who’ve undergone radiation are often at risk for cardiac issues, starting within a couple of years of the end of treatment, and continuing for 20 years or more. Chemotherapy can cause heart problems, too.

Your response: Be aware that your risk of heart attack or coronary blockage is up to 79 percent higher (for high-dose radiation) than it is for other women. Make sure your GP knows of your increased risk, and follow a heart-healthy lifestyle.

Depressed senior woman

Menopausal Side Effects

The issue: Women whose chemotherapy drives them into premature menopause may experience a wide range of long-lasting side effects, both emotional and physical. Taking an aromatase inhibitor as part of long-term treatment exacerbates those side effects.

Your response: Some treatments for menopausal side effects increase your risk of breast cancer recurrence. Speak to your oncologist about which are safe to use.

Thrombus human pathological sample under microscope

Blood clots/stroke

The issue: Women who undergo long-term hormone therapy in the form of tamoxifen are at increased risk for stroke and deep vein thrombosis, blood clots that develop in the legs and travel to the lungs.

Your response: Immediately report any leg pain and/or swelling; chest pain or shortness of breath; numbness; trouble speaking, walking, or seeing; or sudden, severe headache to your doctor.

Senior woman doing sudoku

Chemo brain

The issue: Survivors who’ve had chemotherapy often experience “chemo brain,” a distressing loss of cognitive ability and mental functioning. This usually clears up with time, but many say they never return to their former mental acuity.

Your response: Don’t panic; you’ll probably improve over time. In the meantime, make lists; cut back on multi-tasking; and exercise your brain (crossword puzzles, Sudoku).

Foot in cast

Bone loss

The issue: Taking aromatase inhibitors (Femara, Aromasin, Arimidex) to prevent cancer recurrence increases your risk of osteopenia and osteoporosis – loss of bone density that can lead to weakened bones and fractures.

Your response: Ask your doctor to schedule regular DEXA scans to track any bone changes. If bone loss occurs, ask whether you need bisphosphonate drugs to slow down bone deterioration.

Woman with scarf on her head looking out window

Other cancers

The issue: Women who’ve had radiation are at increased risk for sarcoma, a type of cancer most commonly occurring in bones and cartilage. Women who’ve had chemotherapy are at greater risk for bladder cancer and blood cancers such as leukemia.

Your response: Speak to your oncologist. Identify other cancers for which you might be at risk, then learn the symptoms to watch out for.

Woman touching feet


The issue: Women treated with certain types of chemo drugs, usually Taxol/Taxotere, may experience peripheral neuropathy: long term/permanent tingling and pain in the feet, legs, hands and arms. This can affect balance and use of the hands.

Your response: Ask your oncologist about painkillers and antidepressants to treat pain, or physical therapy, massage, and acupuncture, which some women report helpful.

PJ Hamel
Meet Our Writer
PJ Hamel

PJ Hamel is senior digital content editor and food writer at King Arthur Flour, and a James Beard award-winning author. A 16-year breast cancer survivor, her passion is helping women through this devastating disease. She manages a large and active online survivor support network based at her local hospital and shares her wisdom and experience with the greater community via