Bladder cancers often start in the inner lining of the bladder. If the bladder cancer is not detected early, cancer cells can spread through the lining and into the bladder wall. From there, bladder cancer can spread to other organs surrounding the bladder, such as the prostate or uterus. Another way bladder cancer can spread is through the lymphatic system or blood cells. If this happens, new sites of cancer can develop in other parts of the body that are not close to the bladder.