Microsatellite instability (MSI) doesn’t have anything to do with satellites in the sky. The term actually describes a situation in which there are problems in your DNA that are not fixed, Ursula Matulonis, M.D., tells HealthCentral. Dr. Matulonis is chief of the division of gynecologic oncology at the Susan F. Smith Center for Women's Cancers at Dana-Farber Cancer Institute.
MSI status can affect your treatment of some cancers, including endometrial cancer, and may mean you are at higher risk for other specific cancers. Read on to learn more about how MSI occurs and what it may mean for your endometrial cancer risk.