If you have RRMS and you’re taking a DMT, up your odds of not progressing to SPMS. “Stop smoking, reduce body weight if you’re obese, exercise, and, if you have high blood pressure, diabetes, or high cholesterol, modify your diet to improve these,” advises Dr. Yadav. Tobacco use has been shown to quicken progression to SPMS and disability, so do everything in your power to quit smoking. Plus, there’s mounting evidence that having diabetes or hypertension increases risk of disability, too. So embrace a healthy lifestyle, explore DMTs, and if your symptoms are progressing, tell your doctor immediately.