Treatment Options for Chronic Hives

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In March 2015, the Standards of Care Committee of the British Society for Allergy and Clinical Immunology published guidelines on treatment of chronic urticaria. Here's more information on possible chronic hives treatment options.


Avoid histamine-rich foods

There are a variety of foods that naturally contain histamine. These include fermented alcoholic beverages, fermented foods, vinegar-containing foods, cured meats, lunch meats and hot dogs, soured foods, dried fruit, citrus fruit, aged cheese, nuts, nightshade vegetables, and smoked fish.


Avoid histamine-releasing foods

Certain foods cause the release of histamine that's already present in the body. These include alcohol, bananas, chocolate, cow's milk, nuts, papaya, pineapple, shellfish, strawberries, tomatoes, wheat germ, and many artificial preservatives.


Avoid DAO-blocking foods

Diamine oxidase (DAO) is the main enzyme responsible for breaking down ingested histamine. So if you’re deficient in DAO, you likely have symptoms of histamine intolerance. Here are some DAO-blocking foods: alcohol, energy drinks, black tea, mate tea, and green tea.


Nonsedating anti-H1 antihistamines

Nonsedating anti-H1 antihistamines remain the mainstay of treatment for chronic hives (urticaria). If these medications are ineffective, higher dosages may be tried, or others may be substituted


Eat low-histamine foods

You might be wondering what exactly you _can _eat! Fear not! There are plenty of delicious foods you still can eat, including fresh meat, fresh fish, gluten-free grains, fresh fruit, fresh veggies, dairy substitutes, eggs, and herbal teas.


Stay cool

Overheating and the pressure of belts and tight clothing aggravate chronic hives, so try wearing loose, comfortable clothes.


Avoid aspirin

Aspirin is the most common drug to aggravate urticaria. Aspirin and other NSAIDs can worsen chronic hives in 20 to 30 percent of patients during an active phase, but probably not in remission.



If you suffer from chronic idiopathic urticaria, and other treatment options aren't working, you may want to speak to your doctor about omalizumab. Omalizumab is biologic medication administered via injection and is approved for people 12 years of age and older who remain symptomatic despite treatment with H1-antihistamine therapy.